Our best theories of the Universe strongly indicate that matter and antimatter were created in equal and opposite amounts in the Big Bang, and in a massive mutual annihilation they wiped each other out – almost but not quite completely; there was a tiny (part per billion) bit of matter left over at the end, which now constitutes all of the matter in the Universe. The question of why there was anything left over at all – which is fundamental to our existence - has been an outstanding mystery of cosmology for decades.